B. mallei - agent of glanders, a zoonosis from equines - reported therapeutic agent, sulfadiazine - other antibiotics should be considered and evaluated
B. pseudomallei - agent of melioidosis - reported therapetic agents, ceftazidime, co-trimoxazole, imipenem, chloramphenicol
B. cepacia, B. gladioli, B. multivorans, B. vietnamiensis - associated infections include lung infection, bacteraemia, endocarditis, septic arthritis, UTI - clinical significance of the various taxa in cystic fibrosis patients is unclear - reported therapies, ureidopenicillins, ceftazidime, aztreonam, carbapenems, fluoroquinolones, co-trimoxazole
B. cepacia, B. gladioli, B. mallei, B. pseudomallei previously classified as Pseudomonas spp.
Burkholderia ssp. are resistant to aminoglycosides
References - Gessner, A.R., Mortensen, J.E. (1990). Pathogenic factors of Pseudomonas cepacia isolates from patients with cystic fibrosis. J. med. microbiol. 33, 115-120. - Glass, S., Govan, J.R.W. (1986). Pseudomonas cepacia - fatal pulmonary infection in a patient with cystic fibrosis. J. Infect. 13, 157-158. - Miller, R., Pannell, L., Ingalls, M.S. (1948). Experimental chemotherapy in glanders and melioidosis. Am. J. Hyg. 47, 205-213. - Dance, D.A.B. (1990). Melioidosis. Rev. med. Microbiol. 1, 143-150. - Dance, D.A.B. (1991). Melioidosis: the tip of the iceberg? Clin. Microbiol. Rev. 4, 52-60.
